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FBXO5 Mouse anti-Human, Clone: EMI1/1176, Abnova™

Catalog No. 89934123 Shop All Abnova Corporation Products
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89-934-123 100 μg
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Catalog No. 89-934-123 Supplier Abnova Corporation Supplier No. MAB13275
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Description

Mouse monoclonal antibody raised against partial recombinant human FBXO5.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Specifications

Antigen FBXO5
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Monoclonal
Clone EMI1/1176
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant human FBXO5.
Dilution Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Western Blot (1-2 ug/mL) The optimal working dilution should be determ
Formulation In 1mM PBS (0.05% BSA, 0.05% sodium azide).
Gene Alias EMI1/FBX5/Fbxo31
Gene Symbols FBXO5
Host Species Mouse
Immunogen Recombinant protein corresponding to 203 residues around amino acids 1-250 of human FBXO5.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26271
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG2a κ
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