Invitrogen™ FBXO8 Monoclonal Antibody (OTI11F6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526889

Catalog No. PIMA526889

Description

FBXO8 Monoclonal Antibody for Western Blot, IHC (P)

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Specifications

• Antigen: FBXO8
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9NRD0
• Gene Symbols: Fbxo8
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-231 of FBXO8 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI11F6
• Conjugate: Unconjugated
• Gene: Fbxo8
• Gene Alias: DC10; F-box only protein 8; F-box protein 8; F-box protein Fbx8; F-box/SEC7 protein FBS; FBS; Fbx8; FBXO8; UNQ1877/PRO4320
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26269
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid