FBXO8 Mouse anti-Human, Clone: OTI9G5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF807550

Catalog No. 50-166-8329

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

Specifications

• Antigen: FBXO8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: FBXO8
• Gene Alias: DC10, FBS, FBX8
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26269
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI9G5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9NRD0
• Gene Symbols: FBXO8
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-231 of human FBXO8 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1