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Invitrogen™ FBXO8 Polyclonal Antibody
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Catalog No. PIPA530512
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100 μL
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PIPA530512 100 μL
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Catalog No. PIPA530512 Supplier Invitrogen™ Supplier No. PA530512
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Raji, JC. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (92%), Xenopus laevis (91%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FBXO8
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Fbxo8
Gene Accession No. Q9NRD0, Q9QZN3
Gene Alias DC10; F-box only protein 8; F-box protein 8; F-box protein Fbx8; F-box/SEC7 protein FBS; FBS; Fbx8; FBXO8; UNQ1877/PRO4320
Gene Symbols Fbxo8
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human FBXO8. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26269, 50753
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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