Invitrogen™ FBXW11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100524

Catalog No. PIPA5100524

Description

Antibody detects endogenous levels of total FBXW11.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Specifications

• Antigen: FBXW11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fbxw11
• Gene Alias: 2310065A07Rik; AA536858; beta-transducin repeat-containing protein 2; BTRC2; BTRCP2; F-box and WD repeat domain containing 11; F-box and WD repeats protein beta-TrCP2; F-box and WD-40 domain protein 11; F-box and WD-40 domain protein 1B; F-box protein Fbw1b; F-box/WD repeat-containing protein 11; F-box/WD repeat-containing protein 1B; Fbw11; FBW1B; FBXW11; Fbxw1b; homologous to Slimb protein; HOS; hypothetical protein; KIAA0696
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103583, 23291, 303024
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5SRY7, Q9UKB1
• Gene Symbols: Fbxw11
• Immunogen: A synthesized peptide derived from human FBXW11(Accession Q9UKB1), corresponding to amino acid residues F503-R542.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov