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Invitrogen™ FBXW2 Polyclonal Antibody
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Catalog No. PIPA5100525
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100 μL
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PIPA5100525 100 μL
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Catalog No. PIPA5100525 Supplier Invitrogen™ Supplier No. PA5100525
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total FBXW2.

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FBXW2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FBXW2
Gene Accession No. B2RZ17, Q60584, Q9UKT8
Gene Alias 2700071L08Rik; EMBL:AAI66990.1}; F-box and WD repeat domain containing 2; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; F-box and WD-40 domain-containing protein 2 {ECO:0000312; F-box protein Fbw2; F-box/WD repeat-containing protein 2; FBW2; FBXW2; fbxw2 {ECO:0000312; FWD2; MD6; MGC117371; Protein MD6; RGD:1310460}
Gene Symbols FBXW2
Host Species Rabbit
Immunogen A synthesized peptide derived from human FBXW2(Accession Q9UKT8), corresponding to amino acid residues F382-T432.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26190, 30050, 311881
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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