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FBXW7 Mouse anti-Human, Clone: OTI6H1, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF802822

Encompass_Preferred

Catalog No. 50-166-6181


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of maligcies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.
Specifications

Specifications

FBXW7
Monoclonal
Unconjugated
FBXW7
AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4
Mouse
Affinity Chromatography
RUO
55294
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI6H1
PBS with 8% trehalose and no preservative; pH 7.3
Q969H0
FBXW7
Human recombit protein fragment corresponding to amino acids 1-354 of human FBXW7 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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