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FBXW7 Mouse anti-Human, Clone: OTI6H1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF802822

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of maligcies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.Specifications
FBXW7 | |
Monoclonal | |
Unconjugated | |
FBXW7 | |
AGO, CDC4, FBW6, FBW7, FBX30, FBXO30, FBXW6, SEL-10, SEL10, hAgo, hCdc4 | |
Mouse | |
Affinity Chromatography | |
RUO | |
55294 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI6H1 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q969H0 | |
FBXW7 | |
Human recombit protein fragment corresponding to amino acids 1-354 of human FBXW7 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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