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Invitrogen™ FBXW8 Polyclonal Antibody
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Catalog No. PIPA585451
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100 μL
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PIPA585451 100 μL
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Catalog No. PIPA585451 Supplier Invitrogen™ Supplier No. PA585451
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (80%), Rat (80%), Bovine (81%). Positive Control: U87-MG, SK-N-SH, IMR32. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FBXW8
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene FBXW8
Gene Accession No. Q8N3Y1
Gene Alias 4930438M06Rik; F-box and WD repeat domain containing 8; F-box and WD-40 domain protein 8; F-box and WD-40 domain-containing protein 8; F-box only protein 29; F-box protein FBX29; F-box/WD repeat-containing protein 8; FBW6; FBW8; Fbx29; FBXO29; FBXW6; FBXW8; LOW QUALITY PROTEIN: F-box/WD repeat-containing protein 8; MGC33534
Gene Symbols FBXW8
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human FBXW8. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26259
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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