Fc epsilon RI alpha Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6762	Proteintech Group Inc 109801AP150UL	150 μL

Description

FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one beta and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.

Specifications

• Antigen: Fc epsilon RI alpha
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P12319, P20489
• Gene ID (Entrez): 14125, 2205
• Immunogen: Fc epsilon RI alpha Fusion Protein Ag1398
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: FCER1A

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Fc epsilon RI alpha, FCE1A, FCER1A, FcERI, FceRIa, IgE Fc receptor subunit alpha
• Gene Symbols: FCER1A
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody