Invitrogen™ FCAR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121219

Catalog No. PIPA5121219

Description

Positive test controls include: 293T. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein. Immunogen sequence: LMIIKNSTYR EIGRRLKFWN ETDPEFVIDH MDANKAGRYQ CQYRIGHYRF RYSDTLELVV TGLYGKPFLS ADRGLVLMPG ENISLTCSSA HIPFDRFSLA KEGELSLPQH QSGEHPANFS LGPVDLNVSG IYRCYGWYNR SPYLWSFPSN ALELVVTDSI HQDYTTQNLI RMAVAGLVLV ALLAILVENW HSHTALNKEA SADVAEPSWS QQMCQPGLTF ARTPSVCK.

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: FCAR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fcar
• Gene Alias: CD89; CTB-61M7.2; Fc alpha receptor; Fc fragment of IgA receptor; Fc fragment of IgA, receptor for; FcalphaRI; FCAR; IgA Fc receptor; immunoglobulin A Fc receptor; immunoglobulin A Fc receptor transcript variant 1; immunoglobulin A Fc receptor transcript variant 3; immunoglobulin A Fc receptor transcript variant 7; immunoglobulin A Fc receptor transcript variant 9; immunoglobulin A Fc receptor transcript variant deltaEC1; immunoglobulin A Fc receptor transcript variant deltaEC1 delta TM/C; immunoglobulin alpha Fc receptor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2204
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.66 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P24071
• Gene Symbols: Fcar
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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