FCER1A Mouse anti-Human, Clone:1F2A9, Abnova™

Catalog No.	Quantity
89-334-525	100 μg

Catalog No. 89-334-525 Supplier Abnova Corporation Supplier No. MAB17840

Description

Mouse monoclonal antibody raised against recombinant human FCER1A.

The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM]

Specifications

• Antigen: FCER1A
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 1F2A9
• Conjugate: Unconjugated
• Description: Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
• Dilution: ELISA (1:10000)
  Flow Cytometry (1:200-400)
  Western Blot (1:100-1:500)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: FCER1A
• Gene Alias: FCE1A, FcERI
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 42-103 of human FCER1A from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 2205
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1