FCER2 Mouse anti-Human, Clone: OTI6C2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF801554

Catalog No. 50-166-5633

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.

Specifications

• Antigen: FCER2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: FCER2
• Gene Alias: BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2208
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6C2
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P06734
• Gene Symbols: FCER2
• Immunogen: Human recombit protein fragment corresponding to amino acids 48-321 of human FCER2 produced in SF9 Cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a