Invitrogen™ FCHO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531696

Catalog No. PIPA531696

Description

Recommended positive controls: HCT116. Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (81%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FCHO2 (FCH domain only 2) is a ubiquitously expressed member of the FCFBS superfamily characterized by FES-CIP4 homology (FCH) domain, an FBH domain, and an SH3 domain. Both FCHO2 and the related protein FCHO1 are mediators of clathrin-mediated endocytosis, acting to sculpt the initial bud site and recruit the clathrin machinery for clathrin-coated vesicle formation. FCHO2 binds to Eps15, an important adaptor protein in clathrin-mediated endocytosis.

Specifications

• Antigen: FCHO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FCHO2
• Gene Alias: 5832424M12Rik; AA387320; F-BAR domain only protein 2; FCH domain only 2; FCH domain only protein 2; FCHO2; RGD1565396
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115548
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.89 mg/mL
• Formulation: 0.1M Tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q0JRZ9
• Gene Symbols: FCHO2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 183 of Human FCHO2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG