Invitrogen™ FCRL1 Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547912

Catalog No. PIPA547912

Description

In direct ELISAs, less than 3% cross-reactivity with recombinant human FCRL1/FcRH1 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Fc receptor-like 1 (FCRL1) is a gene situated on chromosome 1q23, encoding a protein that is part of the Fc receptor-like family, which shares structural similarities with classical Fc receptors involved in immune responses. FCRL1 is predominantly expressed in B lymphocytes and is thought to play a role in the regulation of immune functions, particularly those associated with B cell development and differentiation. Although its precise biological function is not fully understood, it is believed to act as an immunomodulatory receptor that could influence B cell signaling pathways. The expression patterns of FCRL1 suggest possible involvement in autoimmune disorders and immune system modulation, potentially contributing to pathological conditions when dysregulated. Research into FCRL1 and other Fc receptor-like proteins continues to explore their contributions to immune homeostasis and potential as therapeutic targets in diseases involving B cell dysfunction.

Specifications

• Antigen: FCRL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fcrl1
• Gene Alias: A230020G22Rik; Bxmas1; BXMAS1-like protein 1; BXMAS1-like protein 1b; Bxmh1; Bxmh1b; CD307a; CD307a antigen; fc receptor 1-like protein; fc receptor homolog 1; Fc receptor like 1; Fc receptor-like 1; Fc receptor-like protein 1; Fcrh1; FCRH1DKFZp667O1421; Fcrh1l; Fcrh1s; Fcrl1; FcR-like protein 1; hIFGP1; IFGP family protein 1; IFGP1; immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA5; mBXMH1; mIFGP1
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 229499
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8R4Y0
• Gene Symbols: Fcrl1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse FCRL1/FcRH1 Ala17-Ser219.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG