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Invitrogen™ FCRL2/FCRL5 Monoclonal Antibody (296902)
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Catalog No. PIMA524005
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100 μg
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Catalog No. Quantity
PIMA524005 100 μg
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Catalog No. PIMA524005 Supplier Invitrogen™ Supplier No. MA524005
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Description

Mouse Monoclonal Antibody

Detects human FCRL2/FcRH2 and FCRL5/FcRH5 in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant human FCRL1, FCRL3, and FCRL4 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Fc receptor homologs, also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH2 (FCRL2) may have a regulatory role in normal and neoplastic B cell development. FcRH5 (FCRL5) expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FCRL5 may be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. It also may have an immunoregulatory role in marginal zone B-cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FCRL2/FCRL5
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 296902
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene FCRL2
Gene Accession No. Q96LA5, Q96RD9
Gene Alias RP11-367J7.6, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C
Gene Symbols FCRL2, FCRL5
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human FCRL2/FcRH2 Glu15-Asp395.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79368, 83416
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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