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Invitrogen™ FCRL2 Monoclonal Antibody (7B12A3)

Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA538482
Description
This antibody has been tested in indirect ELISA.
The FCRL2 gene encodes the protein Fc receptor-like 2, which is part of the Fc receptor-like family involved in immune system regulation. FCRL2 is primarily expressed on the surface of B lymphocytes, where it contributes to the modulation of B cell activation and immune responses. As a member of the Fc receptor-like family, FCRL2 is thought to play roles in signaling pathways that influence B cell development, differentiation, and antibody production. It may act as a regulatory receptor that balances immune activation and inhibition, thereby contributing to immune homeostasis and prevention of autoimmunity. The expression of FCRL2 can impact conditions such as autoimmune diseases and B cell-related disorders, where dysregulation of B cell signaling is evident. Research into FCRL2 is ongoing to explore its specific ligand interactions and functional mechanisms, aiming to understand its potential as a therapeutic target for modulating immune responses in diseases characterized by B cell dysfunction.
Specifications
| FCRL2 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| Q96LA5 | |
| FCRL2 | |
| Purified recombinant fragment of human CD307B (aa: extra 20-253) expressed in E. Coli. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Flow Cytometry, Western Blot | |
| 7B12A3 | |
| Unconjugated | |
| FCRL2 | |
| CD307b; Fc receptor homolog 2; Fc receptor like 2; Fc receptor-like 2; Fc receptor-like protein 2; FCRH2; FCRL2; FcR-like protein 2; IFGP family protein 4; IFGP4; immune receptor translocation-associated protein 4; immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; IRTA4; RP11-367J7.6; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1; SPAP1; SPAP1A; SPAP1B; SPAP1C; UNQ9236/PRO31998 | |
| Mouse | |
| Protein G | |
| RUO | |
| 79368 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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