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Invitrogen™ FCRL2 Monoclonal Antibody (7B12A3)
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Catalog No. PIMA538482
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100 μg
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Catalog No. Quantity
PIMA538482 100 μg
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Catalog No. PIMA538482 Supplier Invitrogen™ Supplier No. MA538482
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Description

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

The FCRL2 gene encodes the protein Fc receptor-like 2, which is part of the Fc receptor-like family involved in immune system regulation. FCRL2 is primarily expressed on the surface of B lymphocytes, where it contributes to the modulation of B cell activation and immune responses. As a member of the Fc receptor-like family, FCRL2 is thought to play roles in signaling pathways that influence B cell development, differentiation, and antibody production. It may act as a regulatory receptor that balances immune activation and inhibition, thereby contributing to immune homeostasis and prevention of autoimmunity. The expression of FCRL2 can impact conditions such as autoimmune diseases and B cell-related disorders, where dysregulation of B cell signaling is evident. Research into FCRL2 is ongoing to explore its specific ligand interactions and functional mechanisms, aiming to understand its potential as a therapeutic target for modulating immune responses in diseases characterized by B cell dysfunction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FCRL2
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 7B12A3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene FCRL2
Gene Accession No. Q96LA5
Gene Alias CD307b; Fc receptor homolog 2; Fc receptor like 2; Fc receptor-like 2; Fc receptor-like protein 2; FCRH2; FCRL2; FcR-like protein 2; IFGP family protein 4; IFGP4; immune receptor translocation-associated protein 4; immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; IRTA4; RP11-367J7.6; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1; SPAP1; SPAP1A; SPAP1B; SPAP1C; UNQ9236/PRO31998
Gene Symbols FCRL2
Host Species Mouse
Immunogen Purified recombinant fragment of human CD307B (aa: extra 20-253) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79368
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

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