Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ FCRLA (FREB) Monoclonal Antibody (N28.1), eBioscience™

Mouse Monoclonal Antibody

$286.00

Specifications

Antigen FCRLA (FREB)
Clone N28.1
Concentration 0.5 mg/mL
Content And Storage 4°C
Applications Flow Cytometry, Immunohistochemistry
View More Specs

Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-132-08
Encompass_Preferred
View Documents
Invitrogen™
14584782
100 μg
Each of 1 for $286.00
Only null left
Add to Cart
 
Description

Description

Description: The N28.1 monoclonal antibody recognizes the Fc receptor homolog expressed in B cells (FREB), also know as FCRLA or FcRX. FREB is a member of the family of Fc receptors for IgG (FcRg). Unlike FcRg, FREB lacks a transmembrane sequence and has an intracellular localization. FREB has been detected in proliferating and activated B cells, EBV-transformed B cells, germinal center centroblast, follicular lymphoma and the Burkitt's lymphoma cell line Raji. In contrast with published reports, the N28.1 antibody was also able to detect expression of FREB in resting B cells from normal human blood samples. Applications Reported: This N28.1 antibody has been reported for use in intracellular staining followed by flow cytometric analysis, and immunohistochemical staining. (Fluorochrome conjugated N28.1 is recommended for use in intracellular flow cytometry). Applications Tested: This N28.1 antibody has been tested by intracellular staining followed by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.03 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. IC Fixation Buffer (Product # 00-8222-49) and Foxp3/Transcription Factor Staining Buffer (Pr...

Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.
Specifications

Specifications

FCRLA (FREB)
0.5 mg/mL
Flow Cytometry, Immunohistochemistry
Unconjugated
Mouse
RUO
PBS with 0.09% sodium azide; pH 7.2
Q7L513
84824
Primary
Affinity chromatography
N28.1
4°C
Monoclonal
Liquid
IgG1
Human
FCRLA
Fc receptor homolog expressed in B cells (FREB); fc receptor homolog expressed in B-cells; Fc receptor like A; Fc receptor related protein X; Fc receptor-like A; Fc receptor-like and mucin-like 1; fc receptor-like and mucin-like protein 1; Fc receptor-like protein; fc receptor-related protein X; FCRL; FCRL1; FCRLA; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB; UNQ291/PRO329
FCRLA
Antibody
Videos
SDS
Documents

Documents

Product Certifications
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.