Invitrogen™ FDFT1 Recombinant Rabbit Monoclonal Antibody (10H12)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538387

Catalog No. PIMA538387

Description

This antibody has been tested in direct-ELISA.

FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.

Specifications

• Antigen: FDFT1
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 50% glycerol, 150 mM NaCl and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P37268
• Gene Symbols: FDFT1
• Immunogen: A synthesized peptide derived from human FDFT1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 10H12
• Conjugate: Unconjugated
• Gene: FDFT1
• Gene Alias: DGPT; EGK_18680; ERG9; farnesyl diphosphate farnesyl transferase 1; farnesyl diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase 1; FDFT1; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; Squalene synthase; squalene synthetase; SS
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2222
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid