Invitrogen™ FDFT1 Monoclonal Antibody (OTI2F10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525676

Catalog No. PIMA525676

Description

FDFT1 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.

Specifications

• Antigen: FDFT1
• Classification: Monoclonal
• Concentration: 0.93 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P37268
• Gene Symbols: FDFT1
• Immunogen: Full length human recombinant protein of FDFT1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI2F10
• Conjugate: Unconjugated
• Gene: FDFT1
• Gene Alias: DGPT; EGK_18680; ERG9; farnesyl diphosphate farnesyl transferase 1; farnesyl diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase 1; FDFT1; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; Squalene synthase; squalene synthetase; SS
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2222
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid