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FDFT1 Mouse anti-Human, Non-human primate, Clone: OTI2F10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525676

Catalog No. PIMA525676


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Description

Description

FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
Specifications

Specifications

FDFT1
Monoclonal
0.93 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P37268
DGPT, ERG9, SQS, SS, FPP:FPP farnesyltransferase, presqualene-di-diphosphate synthase, squalene synthase, squalene synthetase
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2222, 696396
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI2F10
Unconjugated
FDFT1
Liquid
FDFT1
Full length human recombit protein of FDFT1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human, Non-human primate
Documents
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