FDFT1 Mouse anti-Human, Non-human primate, Clone: OTI2F10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525676
DescriptionFDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|DGPT, ERG9, SQS, SS, FPP:FPP farnesyltransferase, presqualene-di-diphosphate synthase, squalene synthase, squalene synthetase|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of FDFT1 produced in HEK293T cell|
|Human, Non-human primate|
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