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Invitrogen™ FDPS Monoclonal Antibody (C1), Invitrogen™

Catalog No. FEMA551148
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FEMA551148 20 μL
FEMA551147 200 μL
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Catalog No. FEMA551148 Supplier Invitrogen™ Supplier No. MA551148
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Description

Mouse Monoclonal Antibody

The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes. 1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FDPS
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone C1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene FDPS
Gene Accession No. P05369
Gene Alias (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; Ac2-125; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; Fdps; Fdpsl1; FPP synthase; FPP synthetase; FPPS; FPS; geranyltranstransferase; KIAA1293; mKIAA1293; POROK9; testis-specific farnesyl pyrophosphate synthetase
Gene Symbols FDPS
Host Species Mouse
Immunogen Recombinant Rat FDPS protein, Met1-Lys353 (Accession #P05369).
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83791
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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