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Invitrogen™ FDPS Polyclonal Antibody
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Catalog No. PIPA596411
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100 μL
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PIPA596411 100 μL
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Catalog No. PIPA596411 Supplier Invitrogen™ Supplier No. PA596411
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IGGKYNRGLT VVVAFRELVE PRKQDADSLQ RAWTVGWCVE LLQAFFLVAD DIMDSSLTRR GQICWYQKPG VGLDAINDAN LLEACIYRLL KLYCREQPYY LNLIELFLQS SYQTEIGQTL DLLTAPQGNV DLVRFTEKRY KSIVKYKTAF YSFYLPIAAA MYMAGIDGEK EHANAKKILL EMGEFFQIQD DYLDLFGDPS VTGKIGTDIQ DNKCSWLVVQ CLQRATPEQY QILKENYGQK EAEKVARVKA LYEELDLPAV FLQYEEDSYS HIMALIEQYA APLPPAVFLG LARKIYKRRK; Positive Samples: 293T, HepG2, HeLa, MCF7, U-251MG, BxPC-3, Mouse liver, Mouse ovary, Rat liver, Rat testis; Cellular Location: Cytoplasm.

The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes. 1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FDPS
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene FDPS
Gene Accession No. P05369, P14324, Q920E5
Gene Alias (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; Ac2-125; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; Fdps; Fdpsl1; FPP synthase; FPP synthetase; FPPS; FPS; geranyltranstransferase; KIAA1293; mKIAA1293; POROK9; testis-specific farnesyl pyrophosphate synthetase
Gene Symbols FDPS
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 120-419 of human FPS/FDPS (NP_0019951).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110196, 2224, 83791
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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