Invitrogen™ FDPS Recombinant Rabbit Monoclonal Antibody (HL2123)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550388

Catalog No. FEMA550388

Description

FDPS Recombinant Monoclonal Antibody for Western Blot, IHC (P)

The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes. 1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.

Specifications

• Antigen: FDPS
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P05369, P14324, Q920E5
• Gene Symbols: FDPS
• Immunogen: Recombinant fragment of human FDPS.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: HL2123
• Conjugate: Unconjugated
• Gene: FDPS
• Gene Alias: (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; Ac2-125; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; Fdps; Fdpsl1; FPP synthase; FPP synthetase; FPPS; FPS; geranyltranstransferase; KIAA1293; mKIAA1293; POROK9; testis-specific farnesyl pyrophosphate synthetase
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 110196, 2224, 83791
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid