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Invitrogen™ FDPS Recombinant Rabbit Monoclonal Antibody (JE63-33)
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Catalog No. PIMA544777
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100 μL
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PIMA544777 100 μL
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Catalog No. PIMA544777 Supplier Invitrogen™ Supplier No. MA544777
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Rabbit Recombinant Monoclonal Antibody

FDPS Recombinant Monoclonal Antibody for Western Blot, Flow

The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes. 1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FDPS
Applications Flow Cytometry, Western Blot
Classification Recombinant Monoclonal
Clone JE63-33
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene FDPS
Gene Accession No. P14324
Gene Alias (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; Ac2-125; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; Fdps; Fdpsl1; FPP synthase; FPP synthetase; FPPS; FPS; geranyltranstransferase; KIAA1293; mKIAA1293; POROK9; testis-specific farnesyl pyrophosphate synthetase
Gene Symbols FDPS
Host Species Rabbit
Immunogen Synthetic peptide within human FDPS aa 370-419/419.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2224
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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