Invitrogen™ FDX1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597254

Catalog No. PIPA597254

Description

Immunogen sequence: MAAAGGARLL RAASAVLGGP AGRWLHHAGS RAGSSGLLRN RGPGGSAEAS RSLSVSARAR SSSEDKITVH FINRDGETLT TKGKVGDSLL DVVVENNLDI DGFGACEGTL ACSTCHLIFE DHIYEKLDAI TDEENDMLDL AYGLTDRSRL GCQICLTKSM DNMTVRVPET VADARQSIDV GKTS; Positive Samples: 293T, K-562, DU145; Cellular Location: Mitochondrion matrix.

The product of this gene is a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to a terminal cytochrome P450. This particular oxidation/reduction system is found in steroidogenic tissues, and is involved with the synthesis of bile acid and vitamin D. In addition to the expressed gene at this chromosomal locus (11q22), there are pseudogenes located on chromosomes 20 and 21. This gene product has been identified in a number of different tissues but all forms have been shown to be identical and are not tissue specific.

Specifications

• Antigen: FDX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FDX1
• Gene Alias: adrenal ferredoxin; Adrenodoxin, mitochondrial; ADX; FDX; Fdx1; ferredoxin 1; ferredoxin-1; Hepatoredoxin; LOH11CR1D; mitochondrial adrenodoxin
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2230
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.6 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P10109
• Gene Symbols: FDX1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-184 of human FDX1/ADX (NP_0041001).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov