Invitrogen™ FECH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597044

Catalog No. PIPA597044

Description

Immunogen sequence: MRSLGANMAA ALRAAGVLLR DPLASSSWRV CQPWRWKSGA AAAAVTTETA QHAQGAKPQV QPQKRKPKTG ILMLNMGGPE TLGDVHDFLL RLFLDRDLMT LPIQNKLAPF IAKRRTPKIQ EQYRRIGGGS PIKIWTSKQG EGMVKLLDEL SPNTAPHKYY IGFRYVHPLT EEAIEEMERD GLERAIAFTQ YPQYSCSTTG; Positive Samples: HepG2, HT-29, Mouse brain; Cellular Location: Matrix side, Mitochondrion inner membrane, Peripheral membrane protein.

The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

Specifications

• Antigen: FECH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FECH
• Gene Alias: AI894116; EPP; FCE; fch; Fcl; FECH; ferrochelatase; ferrochelatase, mitochondrial; Heme synthase; heme synthetase; protoheme ferro-lyase; protoporphyria
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14151, 2235, 361338
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.76 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P22315, P22830
• Gene Symbols: FECH
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FECH (NP_0001312).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov