Invitrogen™ FECH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106355

Catalog No. PIPA5106355

Description

Antibody detects endogenous levels of total FECH.

The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

Specifications

• Antigen: FECH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FECH
• Gene Alias: AI894116; EPP; FCE; fch; Fcl; FECH; ferrochelatase; ferrochelatase, mitochondrial; Heme synthase; heme synthetase; protoheme ferro-lyase; protoporphyria
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14151, 2235, 361338
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P22315, P22830
• Gene Symbols: FECH
• Immunogen: A synthesized peptide derived from human FECH(Accession P22830), corresponding to amino acid residues L348-Q398.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov