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Invitrogen™ Felvizumab Chimeric Recombinant Rabbit Monoclonal Antibody (RSHZ19 (Felvizumab))
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Catalog No. PIMA548054
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200 μg
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PIMA548054 200 μg
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Catalog No. PIMA548054 Supplier Invitrogen™ Supplier No. MA548054
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody is specific for the an epitope located between amino acids 417-432 of conserved fusion (F) protein of RSV.

Felvizumab is a biosimilar that targets RSV. Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps. Its genome consists of single stranded, negative sense RNA that encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein. Its name comes from the fact that F proteins on the surface of the virus cause the membranes on nearby cells to merge, forming syncytia. While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Felvizumab Chimeric
Applications ELISA, Functional Assay
Classification Recombinant Monoclonal
Clone RSHZ19 (Felvizumab)
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Alias SB 209763
Host Species Rabbit
Immunogen This antibody was prepared by the humanization of an F protein-specific murine MAb, RSV19. More specifically, molecular techniques were used to insert the complementarity determining regions from murine RSV19 into a human IgG1 heavy and k light chain-variable domain framework.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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