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Invitrogen™ FEM1A Polyclonal Antibody
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Catalog No. PIPA124858
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100 μg
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Catalog No. Quantity
PIPA124858 100 μg
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Catalog No. PIPA124858 Supplier Invitrogen™ Supplier No. PA124858
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Description

Goat Polyclonal Antibody

Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX10911-PEP).. PA1-24858 is expected to cross react with mouse Fem1C (100% conserved) due to sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FEM1A
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene FEM1A
Gene Accession No. Q4V890, Q9Z2G1
Gene Alias AW611390; DKFZp762M136; EPRAP; fem-1 homolog A; fem-1 homolog a (C. elegans); Fem1a; Fem1aa; FEM1a-A; FEM1-alpha; FEM1-alpha-A; feminization 1 homolog a; feminization 1 homolog a (C. elegans); prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; protein fem-1 homolog A-A; similar to fem-1 homolog a (C.elegans)
Gene Symbols FEM1A
Host Species Goat
Immunogen Peptide with sequence C-HIPEKLETFVSLHR, from the C Terminus.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14154, 316131
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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