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FEM1B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 195441AP150UL

Encompass_Preferred

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Catalog No. 50-173-2446


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Description

Description

The antibody recognize the C-term of FEM1B.

Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1-b. F1Aalpha/FEM1-b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues.
Specifications

Specifications

FEM1B
Polyclonal
Unconjugated
FEM1B
F1A alpha, F1AA, fem 1 homolog b (C. elegans), FEM1 beta, FEM1B, FIAA, KIAA0396, Protein fem 1 homolog B
Rabbit
Antigen Affinity Chromatography
RUO
10116, 14155, 315745
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Western Blot
0.16 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P0C6P7, Q9UK73, Q9Z2G0
Fem1b
Peptide
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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