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Invitrogen™ FEN1 Monoclonal Antibody (A1B12)
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Catalog No. PIMA542534
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100 μL
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PIMA542534 100 μL
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Catalog No. PIMA542534 Supplier Invitrogen™ Supplier No. MA542534
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Description

Mouse Monoclonal Antibody

Positive Control: MCF-7 cell lysate, K562 cell lysate, Daudi cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, human tonsil tissue, human liver carcinoma tissue, human breast carcinoma tissue, K562. Subcellular Location: Nucleolus, nucleoplasm. Mitochondrion.

FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FEN1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone A1B12
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation TBS with 50% glycerol and 0.05% sodium azide; pH 7.4
Gene FEN1
Gene Accession No. P39748, P39749, Q5XIP6
Gene Alias AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2
Gene Symbols FEN1
Host Species Mouse
Immunogen Recombinant protein within human FEN1 aa 150-380.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14156, 2237, 84490
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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