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Invitrogen™ FEN1 Polyclonal Antibody
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Catalog No. PIPA582261
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100 μL
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PIPA582261 100 μL
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Catalog No. PIPA582261 Supplier Invitrogen™ Supplier No. PA582261
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CAALVKAGKV YAAATEDMDC LTFGSPVLMR HLTASEAKKL PIQEFHLSRI LQELGLNQEQ FVDLCILLGS DYCESIRGIG PKRAVDLIQK HKSIEEIVRR LDPNKYPVPE NWLHKEAHQL FLEPEVLDPE SVELKW Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 97%.

FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FEN1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene FEN1
Gene Accession No. P39748, P39749, Q5XIP6
Gene Alias AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2
Gene Symbols FEN1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human FEN1. Recombinant protein control fragment (Product #RP-89493).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14156, 2237, 84490
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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