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  5. Tocris Bioscience™ Fendiline Hydrochloride

Tocris Bioscience™ Fendiline Hydrochloride
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Catalog No. 640750
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Catalog No. Quantity
64-075-0 50 mg
64-071-0 10 mg
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Catalog No. 64-075-0 Supplier Tocris Bioscience™ Supplier No. 6407/50
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Description

Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker

Fendiline Hydrochloride is a K-Ras inhibitor. Selectively inhibits K-Ras localization to the plasma membrane (IC50 = 9.64 μM). Blocks proliferation of cancer cell lines expressing oncogenic mutant K-Ras. Also inhibits L-type calcium channels (IC50 = 17 μM).

Specifications

Chemical Name or Material Ras GTPase Inhibitors
CAS 13636-18-5
Assay Percent Range >98%
Quantity 50 mg
Molecular Formula C23H25N.HCl
Formula Weight Observed MW: 351.91
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