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Tocris Bioscience™ Fenobam
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Catalog No. 238650
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective mGlu5 negative allosteric modulator (NAM)

Potent and selective non-competitive mGlu5 negative allosteric modulator (NAM) that also displays inverse agonist properties; blocks mGlu5 constitutive activity in vitro (IC50 = 87 nM). Acts at an allosteric modulatory site shared with MPEP and binds the mGlu5 receptor with Kd values of 54 and 31 nM for rat and human receptors respectively. Displays anxiolytic activity following oral administration in vivo; also exhibits analgesic properties.

Chemical Identifiers

CAS 57653-26-6
Molecular Formula C11H11ClN4O2
Molecular Weight (g/mol) 266.69

Specifications

Quantity 50 mg
Formula Weight 266.69
Purity >99%
Chemical Name or Material Fenobam

Safety and Handling

Recommended Storage Store at Room Temperature
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