Invitrogen™ FER Monoclonal Antibody (5D2C4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515357

Catalog No. PIMA515357

Description

MA5-15357 targets FER in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human and mouse samples. The MA5-15357 immunogen is purified recombinant fragment of human FER expressed in E. Coli. MA5-15357 detects FER which has a predicted molecular weight of approximately 95kDa.

FER is a member of the FPS/FES family of non-receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. FER is found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes. The group IV cytoplasmic protein-tyrosine kinase Fer has been linked to cellular signaling responses to many different stimuli, including growth factors and cytokines. Data suggest a biological role for Fer in regulation of leukocyte recruitment during the innate immune response.

Specifications

• Antigen: FER
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: P09760, P16591, P70451
• Gene Symbols: FER
• Immunogen: Purified recombinant fragment of human FER expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 14158, 2241, 301737
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 5D2C4
• Conjugate: Unconjugated
• Gene: FER
• Gene Alias: AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

Safety and Handling

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