Invitrogen™ FER Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522992

Catalog No. PIPA522992

Description

This antibody is predicted to react with mouse and canine based on 100% sequence homology. Suggested positive control: Jurkat whole cell lysate.

FER is a member of the FPS/FES family of non-receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. FER is found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes. The group IV cytoplasmic protein-tyrosine kinase Fer has been linked to cellular signaling responses to many different stimuli, including growth factors and cytokines. Data suggest a biological role for Fer in regulation of leukocyte recruitment during the innate immune response.

Specifications

• Antigen: FER
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FER
• Gene Alias: AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2241
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1.12 mg/mL
• Formulation: PBS with 30% glycerol and 0.1% sodium azide
• Gene Accession No.: P16591
• Gene Symbols: FER
• Immunogen: Synthetic peptide made to an internal portion of the human protein (within residues 400-450).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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