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Thermo Scientific™ 5-Fluoroorotic Acid

Detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) dicarboxylase with Thermo Scientific™ 5-Fluoroorotic Acid, used in yeast molecular genetics.

$100.70 - $396.50


Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
FERR0811
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Thermo Scientific™
R0811
1g Each for $100.70
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FERR0812
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Thermo Scientific™
R0812
5g Each for $396.50
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Description

Description

5-Fluoroorotic Acid is a yeast with an active URA3 gene (Ura+) converts 5-FOA to fluorodeoxyuridine, which is toxic to cells (see the scheme below). Yeast strains carrying a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil. 5-FOA is frequently used in experiments with Saccharomyces cerevisiae (URA3), Schizosaccharomyces pombe (URA4 and URA5), Candida albicans (URA3), and E. coli (pyrF).

Convertion of 5-FOA to fluorodeoxyuridine

Convertion of 5-FOA to fluorodeoxyuridine

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