Invitrogen™ Ferritin Monoclonal Antibody (101)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA514733

Catalog No. PIMA514733

Description

MA5-14733 detects Ferritin in ELISA, IP, IF, and RIA applications and shows reactivity to human samples. The MA5-14733 Immunogen is human liver ferritin. MA5-14733 detects ferritin which has a predicted molecular weight of approximately 19kDa. Product MA514733 is a smaller package size of MIF2501 (formerly sold as a Seradyn product).

Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. Ferritin is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in the light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. The ferritin gene has multiple pseudogenes, and ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. Ferritin is a holoenzyme shell with a molecular weight of about 450 kDa, and consists of 24 subunits of two types, H(heavy) and L(light), and capable of storing up to 4,500 atoms of ferric iron.

Specifications

• Antigen: Ferritin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P02792, P02794
• Gene Symbols: FTH1, FTL
• Immunogen: Human liver ferritin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Immunoprecipitation, Radioimmune Assays (RIA), Immunocytochemistry
• Clone: 101
• Conjugate: Unconjugated
• Gene: FTL
• Gene Alias: apoferritin; cell proliferation-inducing gene 15 protein; Ferritin H subunit; ferritin heavy chain; ferritin heavy chain 1; Ferritin heavy chain, N-terminally processed; Ferritin L subunit; ferritin L-chain; ferritin light chain; ferritin light polypeptide-like 3; Ferritin subunit H; ferritin, heavy polypeptide 1; ferritin, light polypeptide; FHC; frih; fril; FTH; Fth1; FTHL6; FTL; HFE5; H-ferritin; HFt; L apoferritin; LFTD; MFH; MGC71996; NBIA3; OK/SW-cl.84; PIG15; placenta immunoregulatory factor; PLIF; proliferation-inducing protein 15
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2495, 2512
• Content And Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov