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Fetuin-A Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501731029 Shop All Proteintech Group Inc Products
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50-173-1029 150 μL
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Catalog No. 50-173-1029 Supplier Proteintech Group Inc Supplier No. 165711AP150UL
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Rabbit Polyclonal Antibody

Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2, two proteins that are involved in chromatin remodeling, suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development.

Specifications

Antigen Fetuin-A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AHSG
Gene Accession No. P02765
Gene Alias A2HS, AHS, AHSG, alpha 2 HS glycoprotein, Alpha 2 Z globulin, Ba alpha 2 glycoprotein, FETUA, Fetuin A, Fetuin-A, HSGA
Gene Symbols AHSG
Host Species Rabbit
Immunogen Fetuin-A Fusion Protein Ag9853
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 197
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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