Invitrogen™ FEZ2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557491

Catalog No. PIPA557491

Description

Immunogen sequence: GSYEERVKRL SVSELNEILE EIETAIKEYS EELVQQLALR DELEFEKEVK NSFISVLIEV QNKQKEHKET AKKKKKLKNG SSQNGKNERS HMPGTYLTTV IPYEKKNGPP SVEDLQILTK ILRAMKEDSE KVPSLLTDYI L Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

Specifications

• Antigen: FEZ2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FEZ2
• Gene Alias: 9030616F16; D17Ertd315e; fasciculation and elongation protein zeta 2; fasciculation and elongation protein zeta 2 (zygin II); fasciculation and elongation protein zeta-2; FEZ2; HUM3CL; pre-T/NK cell associated protein (3Cl); synaptotagmin interacting protein zyginII; Zrp; zygin 2; zygin II; Zygin-2; zygin-related protein types I/II
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9637
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UHY8
• Gene Symbols: FEZ2
• Immunogen: Recombinant protein corresponding to Human FEZ2. Recombinant protein control fragment (Product #RP-102443).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG