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Invitrogen™ FGD1 Polyclonal Antibody
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Catalog No. PIPA541477
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100 μL
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PIPA541477 100 μL
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Catalog No. PIPA541477 Supplier Invitrogen™ Supplier No. PA541477
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Description

Rabbit Polyclonal Antibody

Peptide sequence: HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA Sequence homology: Cow: 86%; Human: 100%; Pig: 86%; Rat: 79%.

FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGD1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene FGD1
Gene Accession No. P98174
Gene Alias AAS; faciogenital dysplasia 1 protein; Faciogenital dysplasia 1 protein homolog; faciogenital dysplasia protein; Fgd1; FGDY; FYVE, RhoGEF and PH domain containing 1; FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia); FYVE, RhoGEF and PH domain-containing protein 1; MRXS16; Rho/Rac GEF; rho/Rac guanine nucleotide exchange factor FGD1; ZFYVE3; zinc finger FYVE domain-containing protein 3
Gene Symbols FGD1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human FGD1 (aa 2-51).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2245
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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