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Invitrogen™ FGD1 Polyclonal Antibody
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Catalog No. PIPA585408
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100 μL
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PIPA585408 100 μL
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Catalog No. PIPA585408 Supplier Invitrogen™ Supplier No. PA585408
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (98%), Rat (98%), Bovine (100%). Positive Control: Target recombinant protein, U87-MG, SK-N-SH, IMR32, SK-N-AS. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGD1
Applications Western Blot
Classification Polyclonal
Concentration 0.85 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene FGD1
Gene Accession No. P98174
Gene Alias AAS; faciogenital dysplasia 1 protein; Faciogenital dysplasia 1 protein homolog; faciogenital dysplasia protein; Fgd1; FGDY; FYVE, RhoGEF and PH domain containing 1; FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia); FYVE, RhoGEF and PH domain-containing protein 1; MRXS16; Rho/Rac GEF; rho/Rac guanine nucleotide exchange factor FGD1; ZFYVE3; zinc finger FYVE domain-containing protein 3
Gene Symbols FGD1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human FGD1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2245
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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