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FGD1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501569826
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50-156-9826 100 μL
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Catalog No. 50-156-9826 Supplier Bethyl Laboratories, Inc Supplier No. A305214A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.

Specifications

Antigen FGD1
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene FGD1
Gene Accession No. P98174
Gene Alias FYVE, RhoGEF and PH domain containing 1, AAS, FGDY, MRXS16, ZFYVE3
Gene Symbols FGD1
Host Species Rabbit
Immunogen Between 50 and 100
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2245
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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