Invitrogen™ FGD5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA546465

Catalog No. PIPA546465

Description

Peptide sequence: FVIKGKVLYT YMASEDKVAL ESMPLLGFTI APEKEEGSSE VGPIFHLYHK Sequence homology: Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%.

FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation. It may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation and may play a role in regulating the actin cytoskeleton and cell shape.

Specifications

• Antigen: FGD5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FGD5
• Gene Alias: C330025N11Rik; Fgd5; FYVE, RhoGEF and PH domain containing 5; FYVE, RhoGEF and PH domain-containing protein 5; mFLJ00274; ZFYVE23; Zinc finger FYVE domain-containing protein 23
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 152273
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6ZNL6
• Gene Symbols: FGD5
• Immunogen: Synthetic peptide directed towards the C-terminal of human FGD5 (aa 1385-1434).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov