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Invitrogen™ FGD5 Polyclonal Antibody
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Catalog No. PIPA590298
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100 μL
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PIPA590298 100 μL
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Catalog No. PIPA590298 Supplier Invitrogen™ Supplier No. PA590298
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YLGLLSENCL HSPRLAAAVR EFEQSVQGGS QTAKHRLLRV VQRLFQYQVL LTDYLNNLCP DSAEYDNTQG ALSLISKVTD RANDSMEQGE NLQKLVHIEH SVRGQGDLLQ PGREFLKEGT LMKVTGKNRR PRHLFLMNDV LLYTYPQKDG KYRLKNTLAV ANMKVSRPVM EKVPYALKIE TSESCLMLSA SSCAERDEWY G; Positive Samples: Mouse brain; Cellular Location: Cell projection, Cytoplasm, Early endosome, Endoplasmic reticulum, Golgi apparatus, cytoskeleton, ruffle membrane.

FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation. It may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation and may play a role in regulating the actin cytoskeleton and cell shape.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGD5
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene FGD5
Gene Accession No. Q80UZ0
Gene Alias C330025N11Rik; Fgd5; FYVE, RhoGEF and PH domain containing 5; FYVE, RhoGEF and PH domain-containing protein 5; mFLJ00274; ZFYVE23; Zinc finger FYVE domain-containing protein 23
Gene Symbols FGD5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human FGD5 (NP_6897493).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 232237
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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