Invitrogen™ FGF13 Monoclonal Antibody (N235/22), PE

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545654

Catalog No. PIMA545654

Description

100% identical to rat, 94% identical to mouse. >80% identity with FGF12A/FHF1A, FGF14A/FHF4A and FGF11A/FHF3A. 1 μg/mL of MA5-45654 was sufficient for detection of FGFA/FHFA (pan) in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 30kDa. Does not cross-react with FGF13B/FHF2B. Cross reacts with FGF12A/FHF1A and FGF14A/FHF4A. This antibody was formerly sold as clone S235-22.

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.

Specifications

• Antigen: FGF13
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48 mM MES, 95.64 mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: P70377, Q92913, Q9ERW3
• Gene Symbols: FGF13
• Immunogen: Synthetic peptide amino acids 2-18 (AAAIASSLIRQKRQARE) of human FHF2A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: N235/22
• Conjugate: PE
• Gene: FGF13
• Gene Alias: AFGF; ECGF; ECGFA; ECGFB; FGF; FGF 1; FGF alpha; FGF13; FGF-13; FGF13A; FGF2; FGFA; Fhf2; FHF-2; Fibroblast growth factor; fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; GLIO703; HBGF 1; HBGF1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14168, 2258, 84488
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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