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Invitrogen™ FGF4 Monoclonal Antibody (2188CT10.1.4)
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Catalog No. PIMA537796
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200 μL
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PIMA537796 200 μL
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Catalog No. PIMA537796 Supplier Invitrogen™ Supplier No. MA537796
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Description

Mouse Monoclonal Antibody

FGF4 Monoclonal Antibody for Western Blot

Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGF4
Applications Western Blot
Classification Monoclonal
Clone 2188CT10.1.4
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Fgf4
Gene Accession No. P08620
Gene Alias FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3
Gene Symbols Fgf4
Host Species Mouse
Immunogen KLH conjugated synthetic peptide between 31-206 amino acids from the human region of human FGF4.
Purification Method Protein G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100758023, 2249
Target Species Human, Hamster
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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