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FGF4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982351
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Catalog No. Quantity
50-198-2351 100 μL
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Catalog No. 50-198-2351 Supplier Bioss Supplier No. BS1256R
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Description

Rabbit Polyclonal Antibody

Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.

Specifications

Antigen FGF4
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Fgf4
Gene Accession No. P08620
Gene Alias FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; Fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; Heparin secretory-transforming protein 1; heparin-binding growth factor 1; Heparin-binding growth factor 4; HST; Hst1; HST-1; HSTF1; Hstf-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; Transforming protein KS3
Gene Symbols Fgf4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human FGF4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2249
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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