Invitrogen™ FGFR1OP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530431

Catalog No. PIPA530431

Description

Recommended positive controls: Jurkat, Raji. Predicted reactivity: Human (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.

Specifications

• Antigen: FGFR1OP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FGFR1OP
• Gene Alias: 4930553O10Rik; centrosomal protein 43; centrosomal protein 43; FGFR1 oncogene partner; CEP43; FGFR1 oncogene partner; FGFR1 oncogene partner 1; FGFR1 oncoprotein partner-like protein; Fgfr1op; fibroblast growth factor receptor 1 oncogene partner; FOP; LOC683722; Unknown (protein for MGC:134294)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11116
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O95684
• Gene Symbols: FGFR1OP
• Immunogen: Recombinant protein encompassing a sequence within the center region of human FGFR1OP. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG