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Invitrogen™ FGFR1OP2 Monoclonal Antibody (1675CT713.89.84)
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Catalog No. PIMA524751
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200 μL
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PIMA524751 200 μL
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Catalog No. PIMA524751 Supplier Invitrogen™ Supplier No. MA524751
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Description

Mouse Monoclonal Antibody

FGFR1OP2 Monoclonal Antibody for Western Blot

FGFR1OP2, also known as FGFR1 oncogene partner 2, is a gene that plays a crucial role in oncogenesis, particularly in myeloproliferative neoplasms. It is known to interact with the FGFR1 (Fibroblast Growth Factor Receptor 1) through chromosomal translocations that can lead to malignancies, such as the formation of the fusion protein FGFR1OP2-FGFR1 in KG-1a leukemic cells. FGFR1OP2 itself is a gene encoding a protein whose function is not entirely understood, but its association with FGFR1 highlights its potential role in oncogenic pathways. The FGFR1 component of the fusion is a receptor tyrosine kinase involved in various cellular processes like cell proliferation, migration, and differentiation. The disruption of these processes through abnormal expression or structural changes such as fusions can lead to uncontrolled cell growth and malignancies. FGFR1 is also frequently studied as a therapeutic target in cancer, given its importance in cellular signaling and cancer progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FGFR1OP2
Applications Western Blot
Classification Monoclonal
Clone 1675CT713.89.84
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene FGFR1OP2
Gene Accession No. Q9CRA9, Q9NVK5
Gene Alias 1500031J01Rik; FGFR1 oncogene partner 2; FGFR1 oncogene partner 2 homolog; FGFR1OP2; fibroblast growth factor receptor 1 oncogene partner 2; HSPC123; HSPC123-like; Wit3.0; Wit3.0_alpha; Wit3.0_beta; wound inducible transcript 3.0; wound inducible transcript 3.0 protein; wound-inducible transcript 3.0 protein
Gene Symbols FGFR1OP2
Host Species Mouse
Immunogen Recombinant protein between 1-172 amino acids of human FGFR1OP2.
Purification Method Protein G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26127, 67529
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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